882-4 Active hydroxy metabolite of atorvastatin increases resistance of human low-density lipoproteins to oxidative modification
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چکیده
منابع مشابه
Effects of Lycopene on the Susceptibility of Low-Density Lipoproteins to Oxidative Modification
The intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. To clarify the possible role of lipophilic antioxidants in prevention of atherosclerosis, we investigated the effects of lycopene on the susceptibility of low-density lipoprotein (LDL) to oxidative modification. In this study, “lycopene” was added to plasma and incubated...
متن کاملEffects of Lycopene on the Susceptibility of Low-Density Lipoproteins to Oxidative Modification
The intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. To clarify the possible role of lipophilic antioxidants in prevention of atherosclerosis, we investigated the effects of lycopene on the susceptibility of low-density lipoprotein (LDL) to oxidative modification. In this study, “lycopene” was added to plasma and incubated...
متن کاملOxidative modification of low density lipoproteins by human polymorphonuclear leukocytes.
Oxidatively modified low density lipoproteins are thought to play an important role in the generation of macrophage-derived foam cells in early atherosclerotic lesions. Cultured endothelial cells, monocytes, macrophages and smooth muscle cells can modify low density lipoproteins, either by a free radical mechanism or by the action of lipoxygenases. Previous studies demonstrated that activated h...
متن کاملVarying susceptibility of different low density lipoproteins to oxidative modification.
The oxidative modification of low density lipoprotein (LDL) may provide a crucial link between plasma LDL and the atherosclerotic lesion. The studies presented herein define time-dependent modifications of LDL constituents caused by CuSO4-catalyzed oxidation. Measurement of the cholesterol content of oxidized LDL by the cholesterol esterase-oxidase assay was found to be inaccurate. The enzymati...
متن کاملeffects of lycopene on the susceptibility of low-density lipoproteins to oxidative modification
the intake of antioxidants intake has been reported to be inversely associated with the incidence of coronary artery disease. to clarify the possible role of lipophilic antioxidants in prevention of atherosclerosis, we investigated the effects of lycopene on the susceptibility of low-density lipoprotein (ldl) to oxidative modification. in this study, “lycopene” was added to plasma and incubated...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2004
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(04)92246-2